Top seed and 2016 champion Djokovic meets Spanish No.17 seed Pablo Carreno Busta in a rematch of their encounter at Flushing Meadows last month, in which the Serb was defaulted. Djokovic had won their three previous clashes.
>ORDER OF PLAY: Day 11 – Wednesday October 7
The winner will lock in a semi-final showdown with either Greek No.5 seed Tsitsipas or 13th seed Andrey Rublev. The Russian denied Tsitsipas in the Hamburg final leading in.
Dual major winner and No.7 seed Kvitova contests her first Roland-Garros quarter-final since 2012 when she meets unseeded German Laura Siegemund. The Czech won their only prior meeting.
Australian Open champion Sofia Kenin will take on fellow American Danielle Collins for her second major semi-final this season. Collins has a 3-0 record against the No.4 seed.