Other rising names, including Stefanos Tsitsipas and Denis Shapovalov will begin their Paris campaigns.
>ORDER OF PLAY: Day 3 - Tuesday, September 28
Women’s second seed Karolina Pliskova opens Court Philippe-Chatrier session when she meets Egyptian qualifier Mayar Sherif.
The French hero of last year’s Billie Jean Cup triumph, Kristina Mladenovic is second on, when she meets German Laura Siegemund.
Former Roland-Garros champion Djokovic begins his bid for Grand Slam No.18 against Swede Mikael Ymer before ninth seed Shapovalov squares off against French veteran Gilles Simon.