After his opening round victory, from a set down against Hungary's Marton Fucsovics, the former world No.6 said that his "resilient mind" has been the key to overcoming the litany of injuries he's experienced since the watershed moments of his career earlier this decade.

One of those was a quarterfinal effort at Roland-Garros in 2021, which also marked his last time on the tournament's biggest Chatrier stage until he sank the hopes of the highest-ranked Frenchman in the draw in 2 hours and 17 minutes.

Despite the unique challenges that come with facing a French player in Paris, Berrettini said afterwards it was one he relished.

“I'm happy,” he told press. “I was happy today when I woke up. Yesterday when I knew that I was playing on centre court, it's been many years.

“I knew the atmosphere would have been amazing, and I just missed playing these kind of matches and enjoying these kind of matches. I'm really proud of the work that I've done to come back and to feel good again.

“Us tennis players are always looking for something more, but I think this is one of those matches that I'm going to remember, you know, because it's a night match against a French player. It feels good.”

And following the exit of world No.1 Jannik Sinner earlier in the day, a player of Berrettini's caliber knows the opportunity that's now in front of him.

No.19 seed Frances Tiafoe is now the highest-ranked player left in the top quarter, and though he might not have a seed next to his name, no man will be overlooking a resurgent Berrettini.

He alluded to as much in his on-court interview. 

"It’s been a journey. Many injuries. Many bad moments. I missed this tournament so much," he said.

"I’m so glad I’m back here. I’m playing really high-level tennis. I’m enjoying my time on court. I have an unbelievable team that supports me. I’m happy for this win. But the tournament is not done yet."